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KMID : 0380020130280040244
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Korean Journal of Biotechnology and Bioengineering
2013 Volume.28 No. 4 p.244 ~ p.248
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Functional Characterization of Callus Extracts of Apple 'Hirosaki' for Cosmetic Materials
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Ko Seung-Hee
Kim Young-Soo
Lee Jin-Hyuck
Kim Il-Hyun
Kim Seung-Beom
Roh Kyung-Baeg
Shin Seung-Woo
Jung Eun-Sun
Park Deok-Hoon
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Abstract
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In order to investigate functional characterization of callus extracts of apple 'Hirosaki' for cosmetic materials, biological activities of its extracts including wrinkle improvement, hair growth, and anti-inflammatory effect were investigated. The callus extract showed similar activity with TGF-β used as positive control at 50 μg/mL in the test of collagen synthesis, and increased 40% of proliferation of hair follicle dermal papilla cells. Especially, in case of anti-inflammatory effect, callus extract inhibited about 50% of COX-2 expression which was known as response for intermediating inflammation, and about 70% of eotaxin-1 production which was increased by atopy dermatitis.
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KEYWORD
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Apple, Callus extract, Plant cell culture, Anti-wrinkle, Hair growth, Anti-inflammation
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